Clean-In-Place / Sterilization-In-Place

Sterile integrity is critical to the manufacturing process. Process vessels and associated piping all along the transfer path, valves, instruments, hoses and filtration skids must be thoroughly cleaned to avoid cross-contamination from cell debris, media, residue from prior batches and cleaning agents.

Our technology incorporates static or dynamic spray balls that work in tandem with temperature, time duration and spray concentration to deliver a thoroughly sanitized process.

CIP is commonly used for cleaning mixing vessels, bioreactors, fermenters & other equipment used in Pharma & Non-Pharma manufacturing. CIP is performed to remove or obliterate previous cell culture batch components. It is used to remove in-process residues, control bioburden, and reduce endotoxin levels within processing equipment and systems. Residue removal is accomplished during CIP with a combination of heat, chemical action & turbulent flow.

Features

• Designed for meeting the cleaning requirements of various equipment.
• Optional return or remote pump.
• Accurate dosing of cleaning agents and temperature control.
• Variable speed control of the pump to ensure cleaning fluid velocity.
• Easy to integrate with other equipment.
• Available with integrated SIP stations for mobile vessels.
• SIP station is fully automated for hands-free SIP of mobile vessels.